How Does Endometriosis Affect Uterine Health?
Patients with mild to moderate endometriosis can often conceive naturally. However, more than 40% of those with advanced stages (especially stages 4 and 5) experience difficulty and delays in getting pregnant. And if pregnancy does occur, it may result in miscarriage or ectopic pregnancy.
But why is that?
Because endometriosis affects the uterus internally in several ways:
🔴 Reduction in implantation-supporting substances: The levels of certain substances responsible for embryo attachment and stability in the uterus are reduced.
🔴 Increased immune and phagocytic cells: These can attack sperm and interfere with embryo implantation, reducing the chances of pregnancy.
🔴 Pelvic adhesions (scar tissue): Chronic inflammation caused by the disease leads to adhesions that distort the natural anatomy of the uterus and surrounding structures, especially the fallopian tubes, which transport eggs from the ovaries to the uterus—creating a kind of “traffic jam” that often requires surgical intervention to restore function.
🔴 Ovarian cysts (chocolate cysts): These cysts form repeatedly and reduce ovarian reserve and egg quality over time.
🔴 Inflammatory response: The body’s reaction to the chronic inflammation associated with endometriosis weakens egg quality and depletes ovarian reserve, which negatively impacts fertility.
So, how can we prepare the body for a successful pregnancy and avoid miscarriage or other obstacles?